Look for the Abandoned Waste Dump on the Far East side of The Mire, and clear out the two level 20 Deathclaws inside.
This secret faction isn’t exactly handing out flyers, so you’ll need to do some digging to get their attention. The Enclave’s mission – to re-establish governmental control of America from key locations, like a secret bunker hidden somewhere deep in Appalachia. Just before the bombs fell, US leadership re-located to a remote Oil Rig off the coast of San Francisco.
There’s a shadow organization known as The Enclave hiding in the region, and if you want to find them, and get on track to gaining access to a nuclear silo, you may find this group interesting. Just because there aren’t any human NPC’s left in Fallout 76, doesn’t mean you can still join some iconic factions.