Note: Although this method shows the steps to disable or change settings of Google Play Music, this problem can be caused by other music related extension like Plex. This will make iTunes as the default program For example, if you are having troubles with iTunes for Windows, click Music and select iTunes from the list. Here are the steps that you need to take in order to make the targeted application as your default application In other words, certain applications will become the default applications for your media key usage.
Windows built-in applications (or other third party applications) taking control over the access of media keys.